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Endocrinology Xagena

Researchers have evaluated the continued safety and efficacy of Testosterone solution 2% ( T-sol ) in a 6-month open label extension study following a 3-month, double-blind, placebo controlled study i ...


Thyroid hormones have a significant impact on heart function, mediated by genomic and non-genomic effects. Consequently, thyroid hormone deficiencies, as well as excesses, are expected to result in pr ...


The prevention of medullary thyroid cancer in patients with multiple endocrine neoplasia type 2 syndrome has demonstrated the ability of molecular diagnosis and prophylactic surgery to improve patient ...


Low plasma 25-Hydroxyvitamin D [ 25(OH)D ] concentration and high body mass index ( BMI ) have been associated with increased risk of diabetes mellitus. Researchers tested the hypotheses that geneti ...


About 60% of patients with type 2 diabetes mellitus achieve remission after Roux-en-Y gastric bypass ( RYGB ) surgery. No accurate method is available to preoperatively predict the probability of remi ...


Sitagliptin ( Januvia ) was used as monotherapy or in combination with Metformin, thiazolidinedione or sulfonylurea. It is not clear whether effects are enhanced or unique when in combination with tra ...


Bilateral macronodular adrenal hyperplasia is a rare cause of primary adrenal Cushing's syndrome. In this form of hyperplasia, hypersecretion of cortisol suppresses the release of corticotropin by pit ...


Congenital adrenal hyperplasia due to 21-hydroxylase deficiency results in cortisol and aldosterone deficiency and is, in its most severe form, lethal. Researchers have assessed the effect of historic ...


Sorafenib ( Nexavar ) holds metastatic thyroid cancer at bay for nearly twice as long as a placebo, according to results of a randomized phase III trial, which was presented during the American Societ ...


Tolvaptan ( Samsca ), an oral antagonist of the vasopressin V(2) receptor, has been found to improve hyponatremia in patients with mixed etiologies. A study has analyzed a subgroup of patients with ...


Results from an investigational hhase 3b clinical study have shown that the addition of Saxagliptin ( Onglyza ) 5 mg to ongoing Insulin therapy ( with or without Metformin ) maintained reductions of g ...


A multicenter study has shown that older men with higher testosterone levels are more likely to have a myocardial infarction or other cardiovascular disease in the future.Study participants were age 6 ...


The EMA ( European Medicines Agency ) is starting a review of the safety of Somatropin-containing medicines authorised centrally or by national procedures in the European Union ( EU ). The review will ...


Prolia ( Denosumab ) binds to RANKL, a transmembrane or soluble protein essential for the formation, function, andsurvival of osteoclasts, the cells responsible for bone resorption. Prolia prevents RA ...


Patients with thyroid cancer who have previously been exposed to radiation, for example, in the workplace, through environmental exposure or for treatment of acne or another condition, appear to have ...